Which strawman to address first?
=> Fauci's organization did, in fact, fund "gain of function" research in Wuhan. Fauci is on the record saying the reward is greater than the risk.
=> Agreed, it was not released as a 'bioweapon,' but, rather, by a type 7 laboratory fuckup ('thank god nobody saw that, I don't want to get fired).
=> It exists, where'd you come up with that?
=> It's more deadly than some strains of the flu, less than others (see the Fort Riley/'Spanish' variant). The biggest problem with SARS-CoV-2, other than the odd death, is the number of patients rendered undead by proliferation of microthrombi, which plug up capillaries in tissues throughout the body and result in scar tissue wherever they land. You may not be dead, but are certainly subject to permanent, irreversible damage.
=> We can keep you from dying pretty reliably, and thus our EUA, but can only halt the progress of the disease and its attendant damage, so our recommendation is that you do everything in your power not to let the disease progress to the point where our therapy is indicated.
=> Wearing a tin foil hat should protect you from radiation damage from 5G, which doesn't appear related to COVID-19 (I have to wonder if someone put that forth as a joke and it caught on).
=> The various vaccines work - sort of, until they wear off and don't, and only if you survive their side effects. I'm sure that, in your decades of work in the Pharma industry, you have been privy to quite a few clinical trials and have a clear understanding of the significance of the data provided thereby. This explains your skepticism and cynicism where, though you take the vaccines, you view them as anything but a panacea.
Is the spike protein, upon whose replication the vaccines are dependent, cytotoxic? Demonstrably.
Is the localized activity of the vaccine, upon which the damaging effects of spike protein generation are limited to the injection site, a sure thing? Not hardly, by a number of mechanisms the vaccine has been shown to migrate and have negative influence throughout the body, sometimes temporary and others fatal.
By the same token that I understand the risks of skydiving and am still willing to throw myself bodily at the nearest planet from a couple of miles up, I have considered the benefit/risk analysis for the vaccine and taken it. I also do everything I can to limit inoculum and to reduce the likelihood of infection if exposed.
The religious fervor expressed regarding this pandemic is both amazing and unsurprising. So far we have not reached the level of bad craziness attained during the Plague of Justinian or during the Black Death but, thanks to the interwebz and the 24 hour news cycle, we're close.
BSBD,
Winsor