ltdiver 3 #1 January 28, 2006 http://www.msnbc.msn.com/id/11062591/ WASHINGTON - The first inhalable version of insulin won federal approval Friday, giving millions of adult diabetics an alternative to some of the injections they now endure. --More on the web site. This is great news!-- ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
peacefuljeffrey 0 #2 January 28, 2006 It's good news, I'm sure. But given that a lot of diabetes is related to people being GROSSLY overweight, I'll bet that more people would be helped if that problem were tackled with gusto... I work with a woman who was overweight enough to qualify for gastric bypass surgery. She has lost a tremendous amount of weight since then (put a little back on, too, but net loss is very high)... Guess what? HER DIABETES WENT AWAY ONCE HER WEIGHT CAME DOWN. --Jeffrey "With tha thoughts of a militant mind... Hard line, hard line after hard line!" Quote Share this post Link to post Share on other sites
ltdiver 3 #3 January 28, 2006 Yes, I absolutely agree about the weight and fitness problem and its association with diabetes. I work in the medical field and see it every day. Often, if we can inspire our patients to get on a fitness program (not only exercise and weight loss, but also proper diet parameters), they can limit their diabetes...sometimes fully. I also work with those who are of thin design, who have diabetes (and alot of times renal disease as well). If they can lessen the stress on their bodies by adopting this less invasive insulin treatment, then I am all for it. Choices. First, lead a healthy lifestyle. Next, seek treatment that is appropriate for your condition. ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
azureriders 0 #4 January 28, 2006 Being grossly overweight is not always the case with diabeties. My dad has never weighed over 150 pounds and he came down with diabeties back in 90. Now he does good to weigh 120. Due to the diabeties he has several other health problems. Red Quote Share this post Link to post Share on other sites
kbordson 8 #5 January 28, 2006 Inhalable insulin would be an amazing forward step! For general information: There are two main types of Diabetes Mellitis (DM) -Type 1 is thought to be due to an infection or some problem making the pancreas incapable of producing enough insulin. You need to take insulin. NEED. Your body does not make it. -Type 2 is a form of insulin resistance. It is generally genetically predisposed, but whether and when you get it depends on the stress you put on your pancreas (weight stresses it a lot). You can try to decrease the insulin resistance by adjusting your diet, using oral meds or you might need insulin. Inhalable insulin is going to help lots of people. Many people with progressive DM-Type 2 don't manage it well because of the difficulty with the injections. My dad hated it, my older sister is only willing to do it now because she's pregnant (and as sister, I can "influence" her ways to do what she needs to better than her doctor.... read in "good family guilt.") But giving yourself a shot with every meal (short acting insulins) or even once a day (newer long acting insulins) can be a frustrating life. It impacts your start of the day, your family, your friends.... Then the kidneys start getting sick, and the eyes, and the extremities (toes, feet)... And as they get sicker, they get more frustrated. Hopefully this will help keep people in better control. Quote Share this post Link to post Share on other sites skinnyshrek 0 #6 January 28, 2006 Right. I have been a diabetic since i was 17. When i was fist diagnosed i was running 6 miles a day big into weights, martial arts everything. Being overweight can induce diabetes. Also, stress can play a huge part. 30-40 years ago diabetes sucked. These days with research it is much easier to handle.http://www.skydivethefarm.com do you realize that when you critisize people you dont know over the internet, you become part of a growing society of twats? ARE YOU ONE OF THEM? Quote Share this post Link to post Share on other sites ltdiver 3 #7 January 28, 2006 Thanks for posting this. People need to be aware that there are many forms that diabetes can take. I know several skydivers who are diabetic. Some are in control of their disease. Others aren't. One I know, who I docked on during JFTC, was misdiagnosed and became deathly sick just a few weeks before this event. Thankfully she found a doctor who listened to her and did some tests. Just in time (for health reasons, too). She got on the proper treatment and her bodily functions came back into line. She came to JFTC and flew flawlessly. I wonder if this inhalable insulin would be of use to her? ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites Tauthier 0 #8 January 28, 2006 My son has had type 1 diabetes since he was six. He's almost 13 now and so burned out on it. He checks his blood sugar 4 or 5 times per day and gives himself shots every time he eats. His endocrinologist wants to put him on a pump but I'd have to pay $1500 for it out of my pocket and I'm not sure I want to do that just yet with all the new developments coming up. I just want a cure! Last year in Japan a mother donated islet cells to her daughter and the daughter is cured of diabetes the last I heard. I believe the cure is near....just hope my son can take care of himself good enough so when the cure comes he doesn't have too many life long problems from all the highs he has. The inhalable is not approved yet for kids. Hopefully it will be soon. I would think it would be much easier to deal with than 4 or 5 shots per day. Teresa Quote Share this post Link to post Share on other sites ltdiver 3 #9 January 28, 2006 In your knowledge, does it seem that boys (men) have a harder time dealing with and controlling diabetes that girls (women) do? Either physically or mentally? I ask this because it seems that I see alot more men having secondary problems stemming from diabetes than I see women who do. ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites kbordson 8 #10 January 28, 2006 I know you were asking Tauthler, but.... I think it's person dependant... not so much male/female. My older sister had a HARD time accepting that she had it and refused to treat it for a while (a bit of stubbornness).... whereas my younger sister took the news in stride, is trying to loose weight, watches her diet, and is trying to use oral meds to control it. It's how you deal with the diagnosis of a chronic lifelong disease that we don't yet have a good "cure" for that is the key. But until the cure... less traumatic treatments would be nice. Quote Share this post Link to post Share on other sites smiles 0 #11 January 28, 2006 hey! I have had type 1 diabetes for 40 years, injected insulin daily, watch my diet of course and exercise... (when I was 10 yrs. old boiled my needles & syringes and tested my urine for blood sugars) Treatment of diabetes way back was stupid for children as laying in a hospital bed with doctors trying to regulate insulin was retarded, tons of fear tactics like "you should not have children, always wear shoes as you will get gangarene and have your feet cut of"...treated like you were a bed ridden sick kid when you actually have nothing wrong.... At least Diabetes can be controlled with regular life style and insulin but inhaling it rather than injecting sounds cool---- Although will still need to poke yourself I understand, The FDA review panel expressed concern about the bulkiness of the dispenser and about some patients who experienced coughing or a slight decrease in lung capacity when using the drug. Pfizer will study the long-term effects of Exubera on the lungs, as well as its safety and effectiveness in patients with lung disease. My understanding is that Type 1 diabetes is an autoimmune disease in which the immune system attacks the beta cells in the pancreas that make insulin. Thus, the pancreas does not make insulin, a hormone which helps turn blood sugar (glucose) into energy. Interesting to me is that my bodies immune system is in overdrive, overproduction of the biological activity of TNFa alpha cells- this causes inflamation (type 1 diabetes, rheumatoid arthritis, crohn's disease, all I am diagnosed with) So- I am treated with insulin, and rather than pumping my body full of anti-inflamatory, I am treated with Remicade infusions (Infliximab) which is a monoclonal antibody, a type of protein that recognizes and binds to and neutralizes the TNF alpha (changes body chemistry- stops inflamation) Remicade is made with human and mouse proteins----(I feel like a science experiment) My diabetes is in way better control since I started Remicade infusions, also crohn's, and rheumatoid arthritis stop flaring up. With 40 years of Diabetes have had no problems associated (eyes are perfect, always heal fine, no kidney problems, heart etc.) And of course 18 yrs. of skydiving has been most benifical to my health! One thing I am famous for at the dz is my snacks (always have food to eat to keep my blood sugars level for skydiving) SMileseustress. : a positive form of stress having a beneficial effect on health, motivation, performance, and emotional well-being. Quote Share this post Link to post Share on other sites ltdiver 3 #12 January 28, 2006 Wow! Thanks for posting! I come across many patients of mine who have rheumatoid arthritis, along with diabetes. I now wonder if they know about the drug you speak of, "Remicade". Is it a common treatment for those who suffer from both of these ailments? Or is it something that doctors need to be more aware of? My heart bleeds for those who have irretractable pain and if it can be helped I wish more physicians would prescribe what you are taking. ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites smiles 0 #13 January 28, 2006 1 infusion of remicade (infliximab - human and mouse proteins 1/2 size of a bottle of insulin) cost $3,800. cnd. According to weight (mine is 130 lbs.) I was infused 3 vials every 3 months for 3 years, and now not in need of more treatments. Huge cost of the drug is most likely why doctors do not prescribe (patients have to afford the cost if medical doesn't cover- hoping this changes in our system.) Line ups of peoples with rheumatoid arthritis are walking away (previously walking cripled up with canes or in wheel chairs) after infusions relieved of all pain-and not having to take anti-inflamatory meds. Also crohn's disease patients defininately have less suffering with inflamation of the intestines, and fistula. Diabetes hard to control when suffering with crohn's, therefore easier to control---(remicade treatments not indicated for Diabetes alone.) All are autoimmune disorders. The cost of remicade infusion with my extended health medical is covered here in B.C. but only 2 provinces in Canada are doing this. I am unsure how it works in U.S.A. but do know it was being used for treament there years before Canada got treatment. SMileseustress. : a positive form of stress having a beneficial effect on health, motivation, performance, and emotional well-being. Quote Share this post Link to post Share on other sites sectaerius 0 #14 January 30, 2006 I also am an insulin dependant diabetic and take 5 or 6 shots per day, every time i eat! I am not too big on trying new things when it comes to diabetic treament, ie, the insulin pen rather than a needle and a bottle...i have been diabetic since i was 9 (15 years) and have seen and tried many different things through the course of my treatment, not many worked (resulting in going right back to the needle and bottle)! But something like this, you almost cant help but think it would have to be a whole lot better! Not to mention easier! So, dont know about you guys but i would sure be willing to give it a try!! Quote Share this post Link to post Share on other sites ltdiver 3 #15 January 30, 2006 Let us know how it goes! A first hand experience speaks volumes. Good luck! ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites skydiver30960 0 #16 January 30, 2006 This is gonna be huge. Why didn't I put every penny I owned in Pfizer last week????? The big issue in my mind is the fact that Pfizer admits they're concerned about the long-term effects. What if it does cause long term lung problems? Will people try to hold Pfizer responsible, even though they were warned? I guess they'll have patients sign a waiver! Elvisio "accept the risk" Rodriguez Quote Share this post Link to post Share on other sites mwabd1 0 #17 January 30, 2006 I don't know about this inhaled insulin, I was diagnosed with type 1 when I was 24.....just got out of the military and it just kinda hit me. I have been on an insulin pump for 3 years now and I don't think that the inhaler will do better than that. i work rotating 12 hour shifts and have 3 young boys so I don't eat any kind of controlled diet but with the pump I keep my A1C's between 6-8 so all in all I'm happy. When I am at the DZ on busy days I make 4-8 video jumps without eating or checking my glucose. As much as Diabetes sucks.....i think Im making the best of it. Quote Share this post Link to post Share on other sites Tauthier 0 #18 January 30, 2006 Having A1C's between 6 and 8 sounds pretty phenomenal to me! My son had a 12 within the past year...brought it down to a 7.9 then last one was a little over 9. I sure wish he would GET IT that he needs to take better care of himself. It's one of the hardest things about being a mom(next to the horror they went through losing their dad that is....)...I feel like the biggest nag....he's in counseling and his counselor is a mom of twin boys that both have diabetes and are now in their 20s and doing good. Keep up the good work!!!! Teresa Quote Share this post Link to post Share on other sites Join the conversation You can post now and register later. If you have an account, sign in now to post with your account. Note: Your post will require moderator approval before it will be visible. Reply to this topic... × Pasted as rich text. 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skinnyshrek 0 #6 January 28, 2006 Right. I have been a diabetic since i was 17. When i was fist diagnosed i was running 6 miles a day big into weights, martial arts everything. Being overweight can induce diabetes. Also, stress can play a huge part. 30-40 years ago diabetes sucked. These days with research it is much easier to handle.http://www.skydivethefarm.com do you realize that when you critisize people you dont know over the internet, you become part of a growing society of twats? ARE YOU ONE OF THEM? Quote Share this post Link to post Share on other sites
ltdiver 3 #7 January 28, 2006 Thanks for posting this. People need to be aware that there are many forms that diabetes can take. I know several skydivers who are diabetic. Some are in control of their disease. Others aren't. One I know, who I docked on during JFTC, was misdiagnosed and became deathly sick just a few weeks before this event. Thankfully she found a doctor who listened to her and did some tests. Just in time (for health reasons, too). She got on the proper treatment and her bodily functions came back into line. She came to JFTC and flew flawlessly. I wonder if this inhalable insulin would be of use to her? ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
Tauthier 0 #8 January 28, 2006 My son has had type 1 diabetes since he was six. He's almost 13 now and so burned out on it. He checks his blood sugar 4 or 5 times per day and gives himself shots every time he eats. His endocrinologist wants to put him on a pump but I'd have to pay $1500 for it out of my pocket and I'm not sure I want to do that just yet with all the new developments coming up. I just want a cure! Last year in Japan a mother donated islet cells to her daughter and the daughter is cured of diabetes the last I heard. I believe the cure is near....just hope my son can take care of himself good enough so when the cure comes he doesn't have too many life long problems from all the highs he has. The inhalable is not approved yet for kids. Hopefully it will be soon. I would think it would be much easier to deal with than 4 or 5 shots per day. Teresa Quote Share this post Link to post Share on other sites
ltdiver 3 #9 January 28, 2006 In your knowledge, does it seem that boys (men) have a harder time dealing with and controlling diabetes that girls (women) do? Either physically or mentally? I ask this because it seems that I see alot more men having secondary problems stemming from diabetes than I see women who do. ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
kbordson 8 #10 January 28, 2006 I know you were asking Tauthler, but.... I think it's person dependant... not so much male/female. My older sister had a HARD time accepting that she had it and refused to treat it for a while (a bit of stubbornness).... whereas my younger sister took the news in stride, is trying to loose weight, watches her diet, and is trying to use oral meds to control it. It's how you deal with the diagnosis of a chronic lifelong disease that we don't yet have a good "cure" for that is the key. But until the cure... less traumatic treatments would be nice. Quote Share this post Link to post Share on other sites
smiles 0 #11 January 28, 2006 hey! I have had type 1 diabetes for 40 years, injected insulin daily, watch my diet of course and exercise... (when I was 10 yrs. old boiled my needles & syringes and tested my urine for blood sugars) Treatment of diabetes way back was stupid for children as laying in a hospital bed with doctors trying to regulate insulin was retarded, tons of fear tactics like "you should not have children, always wear shoes as you will get gangarene and have your feet cut of"...treated like you were a bed ridden sick kid when you actually have nothing wrong.... At least Diabetes can be controlled with regular life style and insulin but inhaling it rather than injecting sounds cool---- Although will still need to poke yourself I understand, The FDA review panel expressed concern about the bulkiness of the dispenser and about some patients who experienced coughing or a slight decrease in lung capacity when using the drug. Pfizer will study the long-term effects of Exubera on the lungs, as well as its safety and effectiveness in patients with lung disease. My understanding is that Type 1 diabetes is an autoimmune disease in which the immune system attacks the beta cells in the pancreas that make insulin. Thus, the pancreas does not make insulin, a hormone which helps turn blood sugar (glucose) into energy. Interesting to me is that my bodies immune system is in overdrive, overproduction of the biological activity of TNFa alpha cells- this causes inflamation (type 1 diabetes, rheumatoid arthritis, crohn's disease, all I am diagnosed with) So- I am treated with insulin, and rather than pumping my body full of anti-inflamatory, I am treated with Remicade infusions (Infliximab) which is a monoclonal antibody, a type of protein that recognizes and binds to and neutralizes the TNF alpha (changes body chemistry- stops inflamation) Remicade is made with human and mouse proteins----(I feel like a science experiment) My diabetes is in way better control since I started Remicade infusions, also crohn's, and rheumatoid arthritis stop flaring up. With 40 years of Diabetes have had no problems associated (eyes are perfect, always heal fine, no kidney problems, heart etc.) And of course 18 yrs. of skydiving has been most benifical to my health! One thing I am famous for at the dz is my snacks (always have food to eat to keep my blood sugars level for skydiving) SMileseustress. : a positive form of stress having a beneficial effect on health, motivation, performance, and emotional well-being. Quote Share this post Link to post Share on other sites
ltdiver 3 #12 January 28, 2006 Wow! Thanks for posting! I come across many patients of mine who have rheumatoid arthritis, along with diabetes. I now wonder if they know about the drug you speak of, "Remicade". Is it a common treatment for those who suffer from both of these ailments? Or is it something that doctors need to be more aware of? My heart bleeds for those who have irretractable pain and if it can be helped I wish more physicians would prescribe what you are taking. ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
smiles 0 #13 January 28, 2006 1 infusion of remicade (infliximab - human and mouse proteins 1/2 size of a bottle of insulin) cost $3,800. cnd. According to weight (mine is 130 lbs.) I was infused 3 vials every 3 months for 3 years, and now not in need of more treatments. Huge cost of the drug is most likely why doctors do not prescribe (patients have to afford the cost if medical doesn't cover- hoping this changes in our system.) Line ups of peoples with rheumatoid arthritis are walking away (previously walking cripled up with canes or in wheel chairs) after infusions relieved of all pain-and not having to take anti-inflamatory meds. Also crohn's disease patients defininately have less suffering with inflamation of the intestines, and fistula. Diabetes hard to control when suffering with crohn's, therefore easier to control---(remicade treatments not indicated for Diabetes alone.) All are autoimmune disorders. The cost of remicade infusion with my extended health medical is covered here in B.C. but only 2 provinces in Canada are doing this. I am unsure how it works in U.S.A. but do know it was being used for treament there years before Canada got treatment. SMileseustress. : a positive form of stress having a beneficial effect on health, motivation, performance, and emotional well-being. Quote Share this post Link to post Share on other sites
sectaerius 0 #14 January 30, 2006 I also am an insulin dependant diabetic and take 5 or 6 shots per day, every time i eat! I am not too big on trying new things when it comes to diabetic treament, ie, the insulin pen rather than a needle and a bottle...i have been diabetic since i was 9 (15 years) and have seen and tried many different things through the course of my treatment, not many worked (resulting in going right back to the needle and bottle)! But something like this, you almost cant help but think it would have to be a whole lot better! Not to mention easier! So, dont know about you guys but i would sure be willing to give it a try!! Quote Share this post Link to post Share on other sites
ltdiver 3 #15 January 30, 2006 Let us know how it goes! A first hand experience speaks volumes. Good luck! ltdiver Don't tell me the sky's the limit when there are footprints on the moon Quote Share this post Link to post Share on other sites
skydiver30960 0 #16 January 30, 2006 This is gonna be huge. Why didn't I put every penny I owned in Pfizer last week????? The big issue in my mind is the fact that Pfizer admits they're concerned about the long-term effects. What if it does cause long term lung problems? Will people try to hold Pfizer responsible, even though they were warned? I guess they'll have patients sign a waiver! Elvisio "accept the risk" Rodriguez Quote Share this post Link to post Share on other sites
mwabd1 0 #17 January 30, 2006 I don't know about this inhaled insulin, I was diagnosed with type 1 when I was 24.....just got out of the military and it just kinda hit me. I have been on an insulin pump for 3 years now and I don't think that the inhaler will do better than that. i work rotating 12 hour shifts and have 3 young boys so I don't eat any kind of controlled diet but with the pump I keep my A1C's between 6-8 so all in all I'm happy. When I am at the DZ on busy days I make 4-8 video jumps without eating or checking my glucose. As much as Diabetes sucks.....i think Im making the best of it. Quote Share this post Link to post Share on other sites
Tauthier 0 #18 January 30, 2006 Having A1C's between 6 and 8 sounds pretty phenomenal to me! My son had a 12 within the past year...brought it down to a 7.9 then last one was a little over 9. I sure wish he would GET IT that he needs to take better care of himself. It's one of the hardest things about being a mom(next to the horror they went through losing their dad that is....)...I feel like the biggest nag....he's in counseling and his counselor is a mom of twin boys that both have diabetes and are now in their 20s and doing good. Keep up the good work!!!! Teresa Quote Share this post Link to post Share on other sites
